| Lactose: 1 g/kg body weight
up to 25g dissolved in 8 oz. (250) ml of water. |
|
Standard: Baseline (0), 60,
120, 180 minutes after the sugar has been ingested or
until H2 /CH4 ppm reach 20/12 over the lowest
preceding measure. |
|
POSITIVE : Breath H2 level
increase of at least 20 ppm over the lowest preceding
value within the test period; Breath CH4 level increases
by at least 12 ppm over the baseline within the test
period; combined increase of at least 15 ppm within the
test period. |
| Fructose: 1g/kg body weight
dissolved in 6-8 oz. of water |
|
Standard: Baseline (0), 60,
90, 120, 180 minutes after the sugar has been ingested |
|
A breath H2 level increase
of at least 20 ppm indicates transport impairment. |
| |
|
|
|
(Note: Fructose malabsorption
is reduced by concomitant glucose or sucrose intake.) |
| Sucrose: 2g/kg body weight
dissolved in 6-8 oz of water |
|
Standard: Baseline (0), 20,
40, 60, 80, 100, 120, 140, 160, 180 minutes after sugar
has been ingested |
|
POSITIVE : Breath H2 level
increase of at least 20 ppm over the lowest preceding
value within the test period; Breath CH4 level increases
by at least 15 ppm over the baseline within the test
period; combined increase of at least 15 ppm within the
test period. |
| d-Xylose: 1g/kg body weight
dissolved in 6-8 oz of water |
|
Standard: Baseline (0), 20,
40, 60, 80, 100, 120, 140, 160, 180 minutes afaater sugar
has been ingested, or until H2 + CH4 reaches
20 over baseline |
|
d-Xylose: Increase of either
H2 or CH4 levels withing 40-60 minutes suggests
bacterial overgrowth. A later increase suggests impairment of intestinal
transport capacity. |
| Sorbitol: 0.25 -0.50g/kg body
weight dissolved in 6-8 oz of water |
|
Standard: Baseline (0), 30,
60, 90, 120, 150, 180 minutes after sugar has been ingested |
|
Breath H2 level increase
after 60 minutes is NORMAL. An increase of over 30 ppm
with cramps indicates sensitivity to sorbitol. |
| Lactulose: 10g dissolved in
6-8 oz of water; 10g (15ml) lactulose syrup |
|
Standard: Baseline (0), 15,
30, 45 60, 90 minutes after the challenge dose has been
taken, or until a positive increase of 12-20 H2 ppm
has been recorded |
|
POSITIVE : Lactulose: Biphasic
pattern in breath H2 levels, two peaks with an early
increase of at least 12 ppm, followed by a second much
larger increase after 1 hour. Two peaks may merge as
an early plateau. |
| Glucose: 70-100g dissolved
in 8 oz of water; 1g/kg body weight |
|
|
|
POSITIVE : Glucose: An increase
of at least 12 ppm breath H2 over the baseline value |
| Lactulose: 0.5g/kg body weight;
10g (15 ml) lactulose syrup |
|
Standard: Beginning 30 minutes
after challenge dose, sample every 10 minutes until either
H2 or CH4 corrected value rises 3 ppm over the
previous level for at least 3 successive time intervals. |
|
Normal mean for Lactulose
testing 70-75 minutes Note: Lactulose shortens intestinal
transit time compared to other tests. |
